A big thank you to Jack and Orsmkirk U11’s football Team who are proud to support the OPA, thank you to this amazing Team. We wish you every success!
Month: November 2019
SSRIs may activate vagus nerve dependent gut-to-brain serotonin signaling.
When Prozac was introduced in 1987, it made a big splash as the first selective serotonin reuptake inhibitor (SSRI) antidepressant for the treatment of major depressive disorder.
Prozac and Sarafem are brand names for a drug called “fluoxetine,” which was first discovered by Eli Lilly in 1972. Since the patent for this drug expired in 2001, fluoxetine is available as a generic FDA-approved prescription for depression, obsessive-compulsive disorder, panic attacks, and some eating disorders.

Historically, most experts and consumers thought fluoxetine worked by inhibiting the reuptake of serotonin in the brain, and that the antidepressant effects of this drug occurred solely from the “neck up.” However, there is still a surprising amount of uncertainty about how SSRIs actually work.
Because 90 percent of the human body’s serotonin is produced in the gut, one current theory is that fluoxetine might boost the amount of serotonin produced “below the neck.”
While the 21st-century debate about SSRIs rages on, a drug-free alternative for treatment-resistant depression called “vagus nerve stimulation (VNS)” was approved by the FDA in 2005 for severe unipolar and bipolar depression. VNS typically involves a small, silver-dollar sized device that is surgically implanted below the skin near the collar bone and works like a pacemaker to stimulate the vagus nerve.

In recent years, researchers at McMaster University’s Brain-Body Institute (Canada) have been investigating a possible link between SSRI antidepressant medications, serotonin levels in the gut, and the role that vagus nerve stimulation might play in boosting gut-to-brain transport of serotonin, which appears to rely on the vagus nerve.
Notably, after a vagotomy—which surgically cuts off gut-to-brain communication via the vagus nerve—SSRIs lose their ability to relieve depression-like symptoms in mice.
As part of the bidirectional gut-brain axis, afferent vagal nerves send signals from the bottom-up. There is reason to believe that these vagus nerve pathways might serve as a type of “serotonin superhighway” between the gut and the brain.
A few days ago, the team at McMaster University—who’ve been conducting research in mice about how SSRIs and the vagus nerve might work in tandem—published a study, “Oral Selective Serotonin Reuptake Inhibitors Activate Vagus Nerve Dependent Gut-Brain Signalling,” in the journal Scientific Reports. The title of this paper sums up the main takeaway of this research: SSRIs may activate the vagus nerve in a way that facilitates gut-brain serotonin signaling.
The authors (McVey Neufeld et al., 2019) describe the context and significance of their findings:
“The vagus nerve is the tenth cranial nerve and is the main afferent pathway connecting the gut to the brain. The vagus nerve can transmit signals to the brain resulting in a reduction in depressive behavior as evidenced by the long-term beneficial effects of electrical stimulation of the vagus in patients with intractable depression.
The vagus is the major neural connection between gut and brain, and we have previously shown that ingestion of beneficial bacteria modulates behaviour and brain neurochemistry via this pathway. Given the high levels of serotonin in the gut, we considered if gut-brain signaling, and specifically the vagal pathway, might contribute to the therapeutic effect of oral selective serotonin reuptake inhibitors (SSRI).”
In a recent interview with Canadian Press published on October 4, 2019, first author Karen-Anne McVey Neufeld said, “This [research] opens the door for examining the gut and the continuous communication that happens between the gut and the brain.” She also said that her team’s findings “suggest the gut may play a larger role in depression than previously believed and the latest research hints at new treatment possibilities in the future.”
Interestingly, McVey Neufeld also told the Canadian Press reporter that another class of antidepressants called “noradrenaline reuptake inhibitors (NRIs)” did not appear to have the same activating effect on the vagus nerve as SSRIs.
“Our results lend weight to the possibility that the vagal pathway connecting gut to brain may provide a novel opportunity for treatment of some psychiatric disorders,” the authors write in the paper’s conclusion. “While further study is both necessary and ongoing, we believe that these findings may point towards a newly invigorated approach in the continuing search for new drugs, dietary supplements or bacteria to beneficially modulate these conditions through their effects on vagal afferent communication.”
The next step for McVey Neufeld and colleagues at McMaster’s Brain-Body Institute is to identify specific gut microbiome factors that may play into mental health and psychological well-being using vagus nerve gut-to-brain signaling.
Why Is the Vagus Nerve Also Called the Wandering Nerve?
If a picture is worth a thousand words, this early anatomical drawing of the vagus nerve (below) speaks volumes. As you scroll down this narrow-and-long image, try visualizing how your vagus nerve facilitates communication along your gut-brain axis as part of a bidirectional feedback loop.

The vagus nerve is also called the “wandering nerve” because it’s the longest nerve in the human body and has countless branches that wind their way from the brainstem all the way down to the lowest part of the intestines, touching most major organs along the way. The vagus nerve modulates the parasympathetic nervous system, which counterbalances the fight-or-flight stress response by eliciting the so-called “relaxation response.”
Over the years, I’ve written dozens of Psychology Today blog posts about the vagus nerve. In 2017, I wrote a 9-part series, “The Vagus Nerve Survival Guide to Combat Fight-or-Flight Urges.” Earlier this year, I wrote a widely-read post, “Longer Exhalations Are an Easy Way to Hack the Vagus Nerve.”
Every time you exhale, your vagus nerve squirts some acetylcholine (also known as “vagusstoff” or “vagus substance”) onto your heart. Vagusstoff acts as a tranquilizer-like substance to slow down beat-to-beat intervals and improves heart rate variability (HRV). Robust vagal tone and higher HRV go hand in hand and are markers for overall psychological and physical well-being.
LinkedIn Image Credit: fizkes/Shutterstock
References
Karen-Anne McVey Neufeld, John Bienenstock, Aadil Bharwani, Kevin Champagne-Jorgensen, YuKang Mao, Christine West, Yunpeng Liu, Michael G. Surette, Wolfgang Kunze & Paul Forsythe. “Oral Selective Serotonin Reuptake Inhibitors Activate Vagus Nerve Dependent Gut-Brain Signalling.” Scientific Reports (First published: October 3, 2019) DOI: 10.1038/s41598-019-50807-8
Article from – Psychology Today https://www.psychologytoday.com/us/blog/the-athletes-way/201910/the-vagus-nerve-may-carry-serotonin-along-the-gut-brain-axis
Epigastric pain is felt in the middle of the upper abdomen, just below the ribcage. Occasional epigastric pain is not usually a cause for concern and may be as simple as a stomach ache from eating bad food.
There are many common digestive problems associated with epigastric pain, as well as a range of other underlying conditions that can cause pain in that area.
Serious cases may be life-threatening, and it is important to work with a doctor to understand the difference between a simple cause of epigastric pain and a more serious underlying condition.
Epigastric pain is a common symptom of an upset stomach, which can be due to long-term gastrointestinal problems or just the occasional bout of indigestion.
1. Indigestion
Indigestion usually occurs after eating. When a person eats something, the stomach produces acid to digest the food. Sometimes, this acid can irritate the lining of the digestive system.
Indigestion can cause symptoms such as:
- burping
- bloating in the abdomen
- feeling full or bloated, even if the portion size was not big
- nausea
These symptoms are often felt alongside epigastric pain. While indigestion happens to everyone from time to time, it may be a sign that a person is intolerant of something they have recently eaten.
2. Acid reflux and GERD
Acid reflux occurs when the stomach acid used in digestion gets backed up in the food pipe (esophagus). Acid reflux usually causes pain in the chest and throat, which is commonly known as heartburn. This feeling may accompany epigastric pain or be felt on its own.
Other common symptoms of acid reflux include:
- indigestion
- burning or aching chest pain
- feeling like there is a lump in the throat or chest
- an acidic or a vomit-like taste in the mouth
- a persistent sore throat or hoarse voice
- a persistent cough
Ongoing acid reflux can damage the food pipe and may cause gastroesophageal reflux disease, or GERD. People with GERD experience epigastric pain and symptoms of indigestion frequently and may require treatment and dietary changes to manage the condition.
Some cases of GERD can lead to a condition called Barrett’s esophagus, where the tissue of the food pipe starts to look like the tissue in the intestines.
3. Overeating
The stomach is very flexible. However, eating more than necessary causes the stomach to expand beyond its normal capacity.
If the stomach expands considerably, it can put pressure on the organs around the stomach and cause epigastric pain. Overeating can also cause indigestion, acid reflux, and heartburn.
4. Lactose intolerance
Lactose intolerance can be another cause of epigastric pain. People who are lactose intolerant have trouble breaking down lactose, a sugar found in milk and other dairy products.
For people with lactose intolerance, eating dairy can cause epigastric pain and other symptoms, including:
- stomach pains
- cramps and bloating
- gas
- nausea or vomiting
- diarrhea
5. Drinking alcohol
Moderate drinking is usually not enough to upset the stomach or intestines. However, drinking too much alcohol at once or excess alcohol over long periods of time can cause inflammation in the lining of the stomach. This inflammation can lead to epigastric pain and other digestive issues.
6. Esophagitis or gastritis
Esophagitis is inflammation of the lining of the food pipe. Gastritis is inflammation of the lining of the stomach. Esophagitis and gastritis can be caused by acid reflux, infections, and irritation from certain medications. Some immune system disorders may also cause inflammation.
If this inflammation is left untreated, it can create scar tissue or bleeding. Other common symptoms include:
- acidic or vomit-like taste in the mouth
- persistent cough
- burning in the chest and throat
- trouble swallowing
- nausea
- vomiting or spitting up blood
- poor nutrition
7. Hiatal hernia
A hiatal hernia occurs when part of the stomach pushes up through the diaphragm and into the chest. This may be due to an accident or weakened diaphragm muscles.
In addition to epigastric pain, other common symptoms of hiatal hernias include:
- sore throat
- irritation or scratchiness in the throat
- trouble swallowing
- gas or especially loud burps
- chest discomfort
Hiatal hernias typically affect older people and may not cause epigastric pain in every case.
8. Peptic ulcer disease
Peptic ulcer disease is when the lining of the stomach or small intestine has been damaged by a bacterial infection or by taking too much of certain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs).
Symptoms of peptic ulcer disease can include epigastric pain and signs of internal bleeding, such as stomach pain, fatigue, and shortness of breath.
9. Gallbladder disorder
Issues with the gallbladder may also cause epigastric pain. Gallstones may be blocking the opening of the gallbladder, or the gallbladder may be inflamed. Specific gallbladder symptoms can include:
- intense pain near the upper right side of the stomach after eating
- clay-colored stool
- jaundice or yellowing skin
- loss of appetite
- gas and bloating
10. Pregnancy
It is very common to feel mild epigastric pain during pregnancy. This is commonly caused by acid reflux or pressure on the abdomen from the expanding womb. Changes in hormone levels throughout pregnancy can also aggravate acid reflux and epigastric pain.
Severe or persistent epigastric pain during pregnancy can be a sign of a more serious condition, so a woman should visit her doctor if experiencing any unusual symptoms.
Diagnosis
Diagnosing the cause of epigastric pain is essential to ensure proper treatment. A healthcare professional will likely ask a series of questions about the pain and any additional symptoms.
If the cause is unclear, they may order tests, including:
- imaging tests, such as X-rays, ultrasound, or an endoscopy
- urine tests to check for infections or bladder disorders
- blood tests
- cardiac tests
Treatment
Treating epigastric pain will vary according to the cause. For instance, if overeating frequently causes epigastric pain, a person may wish to eat smaller portions and ensure they are eating filling foods, such as lean proteins. They may also want to avoid foods that cause gas.
Conditions such as GERD, peptic ulcers, and Barrett’s esophagus may require long-term treatment to manage symptoms. A person should work with their doctor to find a treatment plan that works for them.
If a doctor thinks that taking certain medications is causing the condition, they may recommend switching to a new drug or reducing the dosage.
Over-the-counter or prescription antacids to help reduce frequent acid reflux and epigastric pain caused by stomach acid may be helpful.
Occasional epigastric pain is not usually a cause for concern, but anyone with severe or persistent epigastric pain should see their doctor.
Symptoms that last more than a few days or that occur more than twice a week on a regular basis would be considered persistent.
A visit to the emergency room may be necessary in some cases. Signs of severe complications that require prompt treatment include:
- difficulty breathing or swallowing
- intense pressure or squeezing pain in the chest
- coughing up blood
- blood in the stool
- nausea, vomiting, or diarrhea lasting more than 24 hours in adults
- high fever
- extreme fatigue or loss of consciousness
Many cases of epigastric pain can be treated and prevented by making small changes in the diet or lifestyle. Even chronic symptoms can be managed well with medications and dietary changes.
This article is from Medical News Today – https://www.medicalnewstoday.com/articles/320317.php#when-to-see-a-doctor-
CT scans and MRI scans are two different medical imaging methods that create detailed images of internal body parts, such as bones, joints, and organs.
Doctors order CT scans or MRI scans to help diagnose a wide range of medical conditions. Both types of scan have similar uses, but they produce images in different ways. A CT scan uses X-rays, whereas an MRI scan uses strong magnetic fields and radio waves.
CT scans are more common and less expensive, but MRI scans produce more detailed images.
In this article, we look at the differences between CT scans and MRI scans, as well as their uses, procedures, and safety.
What are they?

CT scans and MRI scans are two different ways of creating detailed images of internal body parts. Doctors can then analyze the images to detect abnormalities, such as fractures in bones, tumors on organs, or joint damage.
Some people refer to a CT scan as a CAT scan, which stands for computerized axial tomography. During a CT scan, a person lies down in a large X-ray machine called a CT scanner. The scanner sends images to a computer.
MRI stands for magnetic resonance imagery. This type of scan uses radio waves and magnets to create images. During an MRI scan, a person lies down in an MRI scanner, which is a machine that creates a constant magnetic field and uses radio waves to bounce off water molecules and fat cells in the body. The scanner also sends images to a computer.
CT scans are more common and less expensive than MRIs. However, MRI scans produce a better image than CT scans.
What are their uses?
The uses of CT and MRI scans are very similar. CT scans are more common because they are less expensive and still provide good detail. A doctor may order an MRI scan when they need to create more accurate, detailed images of the body.
Common uses for a CT scan include examining or looking for:
Doctors commonly use MRI scans to diagnose issues with bones, organs, and joints, including those that affect the:
- ankles
- breasts
- brain
- heart
- joints
- wrists
- blood vessels
Procedure

Both scans usually require the person to lie down on a bed that then moves into the scanner. They will need to remain very still during the scan so that the machines can take clear images.
In both cases, the technicians will leave the room during the scan, but the person can talk to them via an intercom link.
The CT machine takes several X-ray images of the body from different angles. The machine is relatively quiet.
MRI scanners are very noisy, and a technician may offer a person earplugs or headphones to help dull the noise.
Are they safe?
CT scans and MRI scans are both very safe procedures. They may, however, pose slight risks, which differ between the types of scan.
During a CT scan, a person receives a very small dose of radiation, but doctors usually do not consider this harmful.
CT scans use ionizing radiation, which has the potential to affect biological tissues. According to the National Institute of Biomedical Imaging and Bioengineering, the risk of developing cancer from exposure to radiation is generally small.
CT scans and X-ways may not be safe during pregnancy, so doctors might recommend MRI scans or ultrasound scans instead. However, they may still avoid using MRI scans, especially during the first trimester, as a precaution.
MRI scans do not use radiation. They do, however, use strong magnetic fields. People must let their technicians know if they have any form of medical implant, such as a pacemaker, insulin pump, or cochlear implant.
MRI scans produce loud sounds, so people usually wear earplugs or headphones to dull the noise. Individuals with claustrophobia may find MRI scanners difficult to tolerate, although several types of open MRI scanner now exist to get around this problem.
For both CT scans and MRI scans, a doctor may recommend using a contrast dye to make the images clearer. Some people may react badly to certain types of dye.
Choosing the right scan

The uses of MRI and CT scans are very similar. A doctor will decide which scan is appropriate based on a range of factors, such as:
- the medical reason for the scan
- the level of detail that is necessary for the images
- whether a woman is pregnant
- whether a person has claustrophobia or other factors that might make MRI scans difficult for them to tolerate
MRI scans produce a more detailed image of soft tissue, ligaments, or organs. Problems that may be easier to see with an MRI scan include soft tissue damage, torn ligaments, and herniated disks.
Doctors may use a CT scan for creating a generalized image of a body part or for getting images of organs or head fractures.
Summary
CT scans and MRI scans are two methods of imaging internal body parts. They have similar uses but produce pictures in different ways. CT scans use X-rays while MRI scans use strong magnets and radio waves.
A CT scan is generally good for larger areas, while an MRI scan produces a better overall image of the tissue under examination. Both have risks but are relatively safe procedures. A doctor will recommend which scan is right for a person depending on a range of factors.
This article is from Medical News Today – https://www.medicalnewstoday.com/articles/326839.php
Please click on the link below to read more…
The OPA are pleased to welcome aboard two new Trustees –
Mr Javed Sultan – Trustee
MSc MD FRCS Consultant Oesophago-Gastric, Bariatric & Laparoscopic Surgeon and Greater Manchester Clinical Lead for Oesophgo-Gastric Cancer
Javed Sultan started his consultant career in 2014 at Guildford, to help expand and develop the regional oesophago-gastric cancer unit for Surrey. He was a Consultant Surgeon at the largest internationally renowned Northern Oesophago-Gastric Cancer Unit (Newcastle upon Tyne) prior to his appointment at the Royal Surrey County Hospital.
Stephen Brinkworth – Trustee and Treasurer
Born in Cardiff, spent my childhood in the Rhondda Valley, where I attended the local Grammar School, before attending Cardiff University to study economics.
On leaving University, joined NatWest Bank when I spent the next 31 years, initially working in various Branches in S Wales and Bristol, before moving to London in 1984 to a Head Office Dept. Took early retirement in 2003 following the Bank’s acquisition by RBS.
Upon leaving the Bank, joined the local NHS Hospital and spent 6 years as a Project Manager implementing several HR related projects.
In 2010, diagnosed with Oesophageal cancer, but fully recovered following surgery at the Royal Surrey Hospital in Guildford.
A keen sportsman over the years, having played a high level of Soccer and then Squash, and has now progressed to Lawn Bowls, and spends many hours each week on the Bowls green, not only playing but is involved in the greenkeeping duties of his local Club.
Also involved as the Treasurer for a local Probus Club, and still involved with the local Squash Club as Treasurer/Secretary.
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These filling drinks pack up to 35 grams of the macronutrient in one serving!
Believe it or not, you can slurp your way to stronger muscles. While many smoothie recipes are devoid of nutrients and sneak in high amounts of sugar, high-protein smoothies can be a healthy eater’s dream if you blend wisely.
“When sipped at the right times, in the right amount and blended with the right things, smoothies can build and repair lean muscle tissue, help you feel full and satisfied and may help decrease levels of ghrelin, a hunger-related hormone,” says Jenna A. Werner, RD, creator of Happy Slim Healthy.
An ample amount of protein is a must for the biggest benefits, she suggests. “A lot of time smoothies with just fruit and juice or milk can fill us up right away, but they increase blood sugar very quickly—and bring it down even quicker. Add protein to a smoothie for a more balanced food choice. The protein will slow down digestion, keeping you fuller longer, and help prevent sugar spikes and crashes,” Werner explains. If you’re making your smoothie a meal, aim for at least 25 grams of protein. For a snack, 10 or more grams will do, Werner says. Consider adding one of these protein powders to your smoothie for an extra boost of the hunger-curbing macronutrient. So dig out your blender and give these high-protein smoothie recipes a spin.
Yogurt and walnuts crank up the protein level of this dessert-inspired smoothie recipe. With carrots (of course), 1/2 a frozen banana and a date in the mix, you’ll be well on your way to scoring your five a day of fruits and veggies, too.
Protein:13 grams
Get the recipe from Making Thyme for Health »

One sip of this delicious smoothie will transport you to an island vacation. Creamy avocado provides a boost of healthy fats while coconut water helps restore electrolytes after a tough workout. Ginger works to keep tummy woes at bay, and pineapple supplies ample amounts of vitamin C.
Protein: 27.3 grams
Get the recipe from Prevention »
With coconut water for hydration, blueberries for ample antioxidants and Greek yogurt for protein, this is an ideal post-workout snack. “Unsweetened Greek yogurt or plain cottage cheese are both awesome additions to smoothie recipes,” Werner says. “Both can add around 15 to 20 grams of protein with simple, natural ingredients.”
Protein: 17 grams
Get the recipe from Sweet Peas and Saffron »
Yes, oats have protein! A whopping 13 grams per half cup (dried), in fact. A splash of milk and a scoop of yogurt give this cherry smoothie an enviable protein count, while a frozen banana makes it thick and rich.
Protein: 11 grams
Get the recipe from Live Eat Learn »
One ounce of chia seeds, approximately how much is in each serving of this energizing smoothie, offers 5 grams of protein. Yogurt, milk and oats round out the protein-rich line-up of this unique and high-fiber morning meal.
Besides yogurt, “vegetarians can consider blending silken organic tofu into shakes and smoothies, too. You won’t even taste it and it will thicken things nicely,” Werner says.
Protein: 12 grams
Get the recipe from Cotter Crunch »
When you’re craving banana bread but have zero time to bake, turn to this single-serving smoothie. Walnuts, oats and milk provide the protein, while dates sweeten and cinnamon and nutmeg warm up the flavors.
Protein: 11 grams
Get the recipe from A Virtual Vegan »

Fruit smoothies aren’t always protein powerhouses, but this tropical treat is thanks to milk and oats. For an even stronger dose, Werner recommends a scoop of vanilla or strawberry protein powder. “Choose plant-based or all-natural according to your diet. Whichever you choose, powders can add a great amount of protein to your smoothies,” she says.
Protein: 11 grams
Get the recipe from Well Plated »
The perfect treat for the season, this smoothie has 35 grams of protein (in other words, about as much protein as six medium eggs)! You won’t even taste the beans in this cookie-inspired meal replacement once they’re blended with cinnamon, molasses, and ginger. Greek yogurt, flaxseed meal, soy milk and protein powder round out the muscle-building menu.
Protein: 35 grams
Get the recipe from The Healthy Foodie »
Wake up to a buzzy breakfast beverage with a triple-play of protein all-stars: Greek yogurt, protein powder and tahini (sesame seed paste). You’re probably familiar with seeing the latter in hummus, but it’s a subtle smoothie star here, adding just a hint of nuttiness that pairs nicely with the cocoa. Two tablespoons of tahini provides around 6 grams of protein.
Protein: 28 grams
Get the recipe from A Clean Bake »
This vegan-friendly berry smoothie from Jillian Michaels boasts more than 35 grams of protein, thanks to the hemp protein powder and coconut yogurt. Enjoy it as a refreshing post-workout smoothie or an on-the-go breakfast.
Protein: 35.9 grams
Get the recipe from Prevention »
Choose cottage cheese or Greek yogurt to amplify the protein power of this blueberry smoothie. If you’re watching your fat and calorie intake, try another one of Werner’s powdered picks.
“Powdered nut butters offer all the flavor of peanut or almond butters, just with much less fat,” she says. For one teaspoon of almond butter (the amount called for in this high-protein smoothie recipe), trade in one teaspoon of powdered peanut butter mixed with a half teaspoon of water.
Protein: 17 grams
Get the recipe from Cupcakes and Kale Chips »
This high-protein peanut butter breakfast smoothie might just remind you of Chunky Monkey ice cream. Banana, cacao and vanilla protein powder make it taste like the fan-favorite dessert (just without the diet-busting nutrition stats). Be sure to go for natural peanut butter varieties to avoid added sugar.
Protein: 17 grams
Get the recipe from Diabetes Strong »
A drink that tastes like dessert is always a satisfying option—but isn’t always so waistline-friendly. (We see you, Mississippi Mudslides.) This chocolate-cherry option, however, has about twice as much protein as it has fat. Milk provides the protein while dates and cherries provide natural sugars, and spinach tacks on vitamin A, folate, and other nutrients.
Protein: 11 grams
Get the recipe from My Darling Vegan »
Muffins have met their match. Almond butter and milk upgrade the protein level of this creamy, frozen fruit smoothie, while maple syrup makes it taste like a breakfast treat. For even more body benefits, try one of the optional boosters: 1/4 cup of oats or two tablespoons of flaxseed (2 1/2 grams of protein each).
Protein: 10 grams
Get the recipe from Cookie + Kat »
If you could have apple pie in a glass, it would be this smoothie! Made with fiber-rich rolled oats, pecans, cinnamon, and apple cider, this creamy concoction gets its high-protein content from Greek yogurt.
Protein: 13.5 grams
Get the recipe from Prevention »
Christmas is coming…………a unique gift………Order Now
Thrill your walls now with stunning print/s from the OPA’s new art gallery.
Choose from a selection of prints taken and donated by our very own Chairman David Chuter ©
£50 price for each print includes the P & P. – Prints are 20 x 16 inches approx.
See some of the prints below…
To view all the prints on sale, please click here.