The SCAN pathway offers a unique opportunity to access one of the UK’s most comprehensive research infrastructures for non-specific cancer symptoms.

The Oxford Suspected Cancer (SCAN) Pathway aims to reduce the time that patients who have vague symptoms that could be cancer wait to be diagnosed. In doing this, it also aims to increase the number of patients that are diagnosed at an early stage in their illness.

SCAN provides:

  • Extensive clinical, laboratory, and imaging data
  • Biobanked blood and urine samples
  • Support for translational and early detection research

Click here to continue reading.

Brits experiencing a prevalent symptom will be given the opportunity to undergo a groundbreaking cancer test at their local high-street pharmacies. The pioneering “sponge on a string” test is part of a new NHS pilot aimed at preventing oesophageal cancer.

As announced by NHS England, numerous pharmacies across England will introduce “heartburn health checks” to detect Barrett’s oesophagus – a potential precursor to oesophageal cancer, which claims over 8,000 lives in the UK annually. A key sign of this is regularly having heartburn.

During the test, patients swallow a small pill attached to a thread. Upon reaching the stomach, it expands into a sponge roughly the size of a penny. After a few minutes, the sponge is carefully removed, collecting cells from the oesophagus lining, which are then examined in a lab for pre-cancerous changes.

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Run the Nottingham Running Festival Half Marathon for OPA Cancer Charity!

Are you ready to take on a challenge that not only pushes your limits but also helps save lives?

OPA Cancer Charity is calling on supporters, runners, and everyday heroes to participate in the Nottingham Running Festival Half Marathon this summer – and run in aid of those affected by oesophageal and gastric cancers.

Why run for OPA?
Every step you take, every mile you conquer, will help us raise funds to support early diagnosis, provide crucial patient resources, and fund life-saving awareness campaigns. Oesophageal cancer often goes unnoticed until it’s too late – but together, we can change that.

What you’ll get when you run with Team OPA:

  • A free fundraising pack, which includes an OPA Cancer Charity running vest or t-shirt

  • Fundraising support every step of the way

  • The knowledge that you’re making a real difference

Whether you’re an experienced runner or looking to take on your first half marathon, we want you on our team.

📅 Event Date: 3rd Aug 2025
📍 Location: Nottingham Racecourse,Colwick Park, Nottingham NG2 4BE
🎽 Distance: Half Marathon (13.1 miles)

👉 Sign up now to run for OPA and help us beat oesophageal and gastric cancer:
Click here

Join #TeamOPA and make your run matter, together we can make a difference. 

“My mum who is aged 84 was diagnosed last summer around August 2024 with oesophageal cancer and my sisters and I have been looking after her along with carers around day jobs and family life etc.  We were shocked to find out last year that she had around 6 – 12 months to live.  I hope that eventually there will be a cure for this awful disease because she now cannot eat without finding it challenging and her swallowing has been affected, but the protein drinks provided by NHS are helping. I’m really proud to be able to raise some money for this important cause of OPA Cancer Charity, and any sum submitted no matter how small will help.”- Emma Nicholson 

Click here to support Emma’s fundraising page!

The image above is of Matt.

Jonny’s Story – “This year I am raising money for OPA, a charity supporting the lives of those affected by Oesophageal and Gastric Cancer.

In October 2023 Matt, my brother in law was diagnosed with cancer and began treatment immediately. Oesophageal cancer is one of the most aggressive forms and unfortunately Matt lost his battle with Cancer on the 1st August at 10:48pm surrounded by his wife (my sister) Louise, their daughter ( my niece) and my mum.

This type of cancer unfortunately is super at aggressive and a lot of the time only picked up in the later stages. Matts diagnosis was in October, at that time we were told it had already spread around his body into his lymph nodes and he was stage 4 with a 2 year life expectancy.

Matt got 9 months and passed away at 48yrs old.

When going through this kind of journey what becomes apparent is the devastating effects it has, it’s like a tornado, not just the physical aspects but the mental aspect too. On one side your giving it everything you have to beat the unbeatable diagnosis, trying to stay positive and fight, and on the other you’re being told to get everything in order and spend quality time with your family while you have it.

The truth is, we all know someone who has been affected directly or indirectly by some form of Cancer. This year I am aiming to complete 5+ half marathons and looking to finish the year with a 50k+ challenge.” – Jonny Blake

So far, Jonny is taking part in the Royal Parks Half Marathon, Saucony 10k and is on the waiting list of a few others! 

If you would like to support Jonny’s fundraising, click here.

Saucony 10k

“I ran in memory of one of my oldest friends, Paul Greaves that passed away last March (2024). Around Christmas last year he got a bad back and by the time he was diagnosed with oesophageal cancer that had spread, it was too late to save him.  He left a wife and 3 daughters and they nominated the charity after the support they received during this difficult time.  Committing to this really focused my training and after never running more than 1km before 2023, I was up at 5.30am training 5 times a week.

I completed the Hong Kong Standard Chartered Half marathon in under two and a half hours which was my target and I’m grateful to everyone that supported and sponsored me along the way.” – Andrew Woodfine

Abstract

Background

Long-term symptom burden and health-related quality-of-life outcomes after curative oesophageal cancer treatment are poorly understood. Existing tools are cumbersome and do not address the post-treatment population specifically. The aim of this study was to validate the six-symptom LASORS tool for identifying patients after curative oesophageal cancer treatment with poor health-related quality of life and to assess its clinical utility.

Methods

Between 2015 and 2019, patients from 15 UK centres who underwent curative-intent oesophageal cancer treatment, and were disease-free at least 1 year after surgery, were invited to participate in the study and complete LASORS and European Organisation for Research and Treatment of Cancer QLQ-C30 and QLQ-OG25 questionnaires. Receiver operating characteristic curve analysis was used to examine the accuracy of the LASORS tool for identifying patients with poor health-related quality of life.

Results

A total of 263 patients completed the questionnaire. Four of the six LASORS symptoms were associated with poor health-related quality of life: reduced energy (OR 2.13 (95% c.i. 1.45 to 3.13)); low mood (OR 1.86 (95% c.i. 1.20 to 2.88)); diarrhoea more than three times a day unrelated to eating (OR 1.48 (95% c.i. 1.06 to 2.07)); and bloating or cramping after eating (OR 1.35 (95% c.i. 1.03 to 1.77)). The LASORS tool showed good diagnostic accuracy with an area under the receiver operating characteristic curve of 0.858 for identifying patients with poor health-related quality of life.

Conclusion

The six-symptom LASORS tool generated a reliable model for identification of patients with poor health-related quality of life after curative treatment for oesophageal cancer. This is the first tool of its kind to be prospectively validated in the post-esophagectomy population. Clinical utility lies in identification of patients at risk of poor health-related quality of life, ease of use of the tool, and in planning survivorship services.

Read more here.

This article is from British Journal of Surgery | Oxford Academic

My name is James, and I’ve consistently led an active and busy lifestyle. I worked in construction for years, enjoyed the outdoors, and never thought much about my health until one day, I started having trouble swallowing. At first, it seemed like just a minor irritation—food would occasionally get stuck in my throat, and I’d experience some heartburn after meals. But soon, the problem became more persistent, and I found myself losing weight without trying. That’s when I decided to go to the doctor.

After a few tests, I was told that I had oesophageal cancer. The news hit me like a punch to the gut. I was in my mid-50s, and the last thing I ever expected was to face something so serious. I wasn’t a smoker, didn’t drink much, and had always been healthy. My doctor explained that my cancer was in the early stages.

My Diagnosis

When I first heard the diagnosis, it was hard to wrap my head around it. I kept asking myself how this could have happened to me. My family was in shock, too, but they immediately rallied around me. My wife, Katy, especially, became my rock. She made sure I had all the information I needed. She contacted the OPA Cancer Charity, and they provided tremendous support. At the time, I wasn’t sure how I’d get through it, but the support from my family and this charity kept me grounded.

My Treatment Plan

My treatment plan involved a combination of surgery and chemotherapy. The goal was to remove the tumour and ensure that any remaining cancer cells were eradicated with chemotherapy.

The surgery was scheduled first, and I was nervous about what it would entail. I knew it was my best chance for recovery, but that didn’t make it any less intimidating. The surgery went well, but the recovery afterward was tough. I was in a lot of pain, and swallowing became a huge challenge. I couldn’t eat solid food for a while and had to rely on liquid nutrition to get by. It was a difficult adjustment, but I kept telling myself it was temporary—just a step on the path to healing.

Chemotherapy and Radiotherapy

Once I’d healed enough from the surgery, it was time to start chemotherapy and radiotherapy. To be honest, I wasn’t sure what to expect. I’d heard the horror stories of how difficult it could be, and I was nervous about the side effects. The treatments were exhausting—nausea, fatigue, and the feeling that I was constantly drained. There were days when I didn’t know how I was going to make it through the next round, but I kept pushing myself. The helpline at the OPA was a true lifeline for me. I was able to connect with a patient buddy who had been through a similar experience, and it made all the difference.

Post Treatment

I remember the day I got that news that my cancer was in remission – it felt like a weight had been lifted off my shoulders. But as relieved as I was, I knew the real work was just beginning. I had to regain my appetite and adjust to life after treatment.

Swallowing was still difficult, and I had to learn to be patient with my body. Eating small, frequent meals became my new normal. My doctors worked with me to adjust my diet, and slowly, I started feeling more like myself again. I found the OPA literature beneficial.

Looking Ahead

As the months went by, I started to appreciate life in a whole new way. I took nothing for granted anymore. Every day was a gift, and I was determined to make the most of it. My family and I made plans—small things, like walks in the park, little trips away, and cooking meals together. Things I used to do without thinking now felt like a celebration.

I’m still here, still fighting, and still grateful for every moment I have, and this experience has taught me the true power of strength and the importance of never giving up.

Main symptoms of oesophageal cancer

There are many possible symptoms of oesophageal cancer, but they might be hard to spot.

They can affect your digestion, such as:

Other symptoms include:

  • a cough that is not getting better
  • a hoarse voice
  • loss of appetite or losing weight without trying to
  • feeling tired or having no energy
  • pain in your throat or the middle of your chest, especially when swallowing
  • black poo or coughing up blood (although these are uncommon)

If you have another condition, such as gastro-oesophageal reflux disease, you may get symptoms like these regularly.

You might find you get used to them. But it’s important to be checked by a GP if your symptoms change, get worse, or do not feel normal for you.

https://www.nhs.uk/conditions/oesophageal-cancer/symptoms/ 

My name is Anna, and I’ve always been an active, vibrant woman who loved cooking, hiking, and spending time with my family. But one day, I started noticing subtle symptoms—difficulty swallowing, occasional heartburn, and a feeling of something being stuck in my chest. At first, I brushed it off as just indigestion, but as time went on, the symptoms only worsened. Eventually, I decided to see my doctor. After several tests, I received the life-changing news: I had oesophageal cancer.

The Shock of Diagnosis

The news was a complete shock. I never imagined that something as simple as heartburn could lead to such a serious diagnosis. I was overwhelmed with fear and uncertainty about what was to come. I remember feeling paralysed by the unknown, but my family, especially my husband Mark, was right by my side. My doctor explained that my cancer was caught early, which was a good sign, but I knew there was still a long road ahead.

My Treatment

My treatment included surgery to remove part of my oesophagus, followed by chemotherapy and radiotherapy to make sure the cancer was completely gone. The surgery came first, and I won’t lie—I was terrified. I knew it was necessary, but the thought of it was daunting.

The recovery after the surgery was tough. The first few weeks were some of the hardest of my life. I struggled with swallowing, and I felt weak and exhausted. But I had an incredible team of healthcare professionals supporting me—doctors, nutritionists, physiotherapists. Slowly, I began to heal, and though it was hard, I knew it was a step in the right direction.

The Road to Recovery

After several months of treatment, I received the news I had been hoping for: my scans showed that the cancer was in remission.

I focused on rebuilding my strength, both physically and mentally. It wasn’t easy adjusting to new eating habits and managing difficulty with swallowing was a big challenge. I had to learn how to eat smaller, more frequent meals, and take my time with every bite. But with the help of my doctors and dietitians, I learned how to make it work, and eventually, I was able to enjoy food again. It wasn’t the same as before, but it was still something I could appreciate. I found the literature from the OPA Cancer Charity really helpful, I can’t thank them enough.

OPA also put me in touch with a local cancer support group. Meeting others who had been through similar experiences was incredibly comforting. We shared our stories, supported each other, and offered advice and encouragement. It helped me feel connected and gave me even more hope for the future.

Embracing Hope and Resilience

Throughout this journey, hope was my constant companion. Each day of recovery brought its own set of challenges, but also new reasons to be hopeful. Every small victory—feeling less tired, gaining a little weight, or just being able to enjoy a day without needing to rest—became something to celebrate. I realised that cancer didn’t define me. It was just one part of my story.

Today, over a year since my treatment ended, I’m doing better than I could have imagined. I’m back to hiking, cooking meals with my family, and living life with a deeper appreciation. Oesophageal cancer tried to take a lot from me, but it couldn’t take away my hope, my strength, or my will to keep fighting.

Looking back, my journey wasn’t easy, but it’s a testament to the power of recovery and resilience. It shows that even in the face of a difficult diagnosis, there’s always hope—and the possibility of finding joy and strength once again.